efflux-pump

常见例句

• Objective:To explore the role of efflux pump in drug resistance to fluoroquinolones in Stenotrophomonas maltophilia.
  目的:探讨主动外排泵在嗜麦芽寡养单胞菌对氟喹诺酮类药物耐药中的作用。
• The drug-resistance mechaniam of shigella caused by producing inactived enzyme,changing cell walls,target site structure and active efflux pump.
  志贺菌的耐药机制主要是产生灭活酶、细胞壁的改变、主动外排以及作用靶位结构的改变。
• ABSTRACT Objective To investigate the role of efflux pump of Acinetobacter baumannii mutant strains against fluoroquinolones.
  目的探讨主动外排泵在鲍曼不动杆菌诱导突变株对氟喹诺酮类药物敏感性的影响。
• P-glycoprotein is an ATP-driven efflux pump which transport a wide variety of structurally diverse compounds from the cell interior into the extracellular space.
  糖蛋白是一个能量依赖性转运蛋白,能将许多结构不同的化合物逆向转运出细胞。
• The acrAB locus encode the efflux pump AcrAB,which confers multidrug tolerance,controlled by the regulon marRAB. Mutation in the gyrase and topoisomerase IV lead to fluoroquinolones resistance, mainly arise in gyrA and parC genes.
  AcrAB外流泵系统的合成有多重耐药调节子 (marRAB)调控 ,AcrAB与多种抗生素的耐药有关。 拓扑异构酶 (topoisomerase)的突变主要与氟喹诺酮类药物的耐药性有关 ,突变主要发生在gyrA ,parC基因上
• It suggested that the level of resistance of isolates would be related to selecting pressure of fluoroquinolones and induced gene mutations of DNase and topoisomerase IV could not activate AcrAB efflux pump system.
  提示临床分离的鸡大肠杆菌O 78的耐药水平与喹诺酮类药物的选择性压力有关,它诱导了DNA旋转酶和拓扑异构酶IV的基因突变,可能不能激活A crAB外输泵。
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