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Coadministration of hypothalamic PKC- inhibitor rottlerin with OAG prevented the ability of OAG to activate PKC- and lower glucose production. 下丘脑蛋白激酶C抑制剂卡马拉素和OAG同时给药会抑制OAG活化蛋白激酶C的能力并降低葡萄糖的生成。